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Genetic Background Influences Susceptibility to Chemotherapy-Induced Hematotoxicity

Hematotoxicity is a life-threatening side effect of many chemotherapy regimens. While clinical factors influence patient responses, genetic factors may also play an important role. We sought to identify genomic loci that influence chemotherapy-induced hematotoxicity by dosing Diversity Outbred mice...

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Detalles Bibliográficos
Autores principales:	Gatti, Daniel M., Weber, Susanne N., Goodwin, Neal C., Lammert, Frank, Churchill, Gary A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729066/ https://www.ncbi.nlm.nih.gov/pubmed/28607509 http://dx.doi.org/10.1038/tpj.2017.23

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