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Multimodal Imaging in Rat Model Recapitulates Alzheimer's Disease Biomarkers Abnormalities

Imaging biomarkers are frequently proposed as endpoints for clinical trials targeting brain amyloidosis in Alzheimer's disease (AD); however, the specific impact of amyloid-β (Aβ) aggregation on biomarker abnormalities remains elusive in AD. Using the McGill-R-Thy1-APP transgenic rat as a model...

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Detalles Bibliográficos
Autores principales:	Parent, Maxime J., Zimmer, Eduardo R., Shin, Monica, Kang, Min Su, Fonov, Vladimir S., Mathieu, Axel, Aliaga, Antonio, Kostikov, Alexey, Do Carmo, Sonia, Dea, Doris, Poirier, Judes, Soucy, Jean-Paul, Gauthier, Serge, Cuello, A. Claudio, Rosa-Neto, Pedro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729194/ https://www.ncbi.nlm.nih.gov/pubmed/29097597 http://dx.doi.org/10.1523/JNEUROSCI.1346-17.2017

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