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Graded Elevation of c-Jun in Schwann Cells In Vivo: Gene Dosage Determines Effects on Development, Remyelination, Tumorigenesis, and Hypomyelination

Schwann cell c-Jun is implicated in adaptive and maladaptive functions in peripheral nerves. In injured nerves, this transcription factor promotes the repair Schwann cell phenotype and regeneration and promotes Schwann-cell-mediated neurotrophic support in models of peripheral neuropathies. However,...

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Detalles Bibliográficos
Autores principales:	Fazal, Shaline V., Gomez-Sanchez, Jose A., Wagstaff, Laura J., Musner, Nicolo, Otto, Georg, Janz, Martin, Mirsky, Rhona, Jessen, Kristján R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729195/ https://www.ncbi.nlm.nih.gov/pubmed/29109239 http://dx.doi.org/10.1523/JNEUROSCI.0986-17.2017

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