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Identification of Ser465 as a novel PINK1 autophosphorylation site

BACKGROUND: PINK1 (PTEN-induced putative kinase 1) gene is the causal gene for recessive familial type 6 of Parkinson’s disease (PARK6), which is an early-onset autosomal recessive inherited neurodegenerative disease. PINK1 has been reported to exert both autophosphorylation and phosphorylation acti...

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Detalles Bibliográficos
Autores principales: Guo, Ji-feng, Yao, Ling-yan, Sun, Qi-ying, Cui, Yi-ting, Yang, Yang, Xu, Qian, Yan, Xin-xiang, Tang, Bei-sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729251/
https://www.ncbi.nlm.nih.gov/pubmed/29255601
http://dx.doi.org/10.1186/s40035-017-0103-7