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Synovial tissue macrophages: friend or foe?

Healthy synovial tissue includes a lining layer of synovial fibroblasts and macrophages. The influx of leucocytes during active rheumatoid arthritis (RA) includes monocytes that differentiate locally into proinflammatory macrophages, and these produce pathogenic tumour necrosis factor. During sustai...

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Detalles Bibliográficos
Autores principales: Kurowska-Stolarska, Mariola, Alivernini, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729306/
https://www.ncbi.nlm.nih.gov/pubmed/29299338
http://dx.doi.org/10.1136/rmdopen-2017-000527