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Impact of killer-immunoglobulin-like receptor and human leukocyte antigen genotypes on the efficacy of immunotherapy in acute myeloid leukemia

Interactions between killer-immunoglobulin-like receptors (KIRs) and their HLA class I ligands are instrumental in natural killer (NK) cell regulation and protect normal tissue from NK cell attack. Human KIR haplotypes comprise genes encoding mainly inhibitory receptors (KIR A) or activating and inh...

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Detalles Bibliográficos
Autores principales:	Bernson, E, Hallner, A, Sander, F E, Wilsson, O, Werlenius, O, Rydström, A, Kiffin, R, Brune, M, Foà, R, Aurelius, J, Martner, A, Hellstrand, K, Thorén, F B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729331/ https://www.ncbi.nlm.nih.gov/pubmed/28529313 http://dx.doi.org/10.1038/leu.2017.151

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