E-selectin ligands recognised by HECA452 induce drug resistance in myeloma, which is overcome by the E-selectin antagonist, GMI-1271

Multiple myeloma (MM) is characterized by the clonal expansion and metastatic spread of malignant plasma cells to multiple sites in the bone marrow (BM). Recently, we implicated the sialyltransferase ST3Gal-6, an enzyme critical to the generation of E-selectin ligands, in MM BM homing and resistance...

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Detalles Bibliográficos
Autores principales: Natoni, A, Smith, T A G, Keane, N, McEllistrim, C, Connolly, C, Jha, A, Andrulis, M, Ellert, E, Raab, M S, Glavey, S V, Kirkham-McCarthy, L, Kumar, S K, Locatelli-Hoops, S C, Oliva, I, Fogler, W E, Magnani, J L, O'Dwyer, M E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729350/
https://www.ncbi.nlm.nih.gov/pubmed/28439107
http://dx.doi.org/10.1038/leu.2017.123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729350/
https://www.ncbi.nlm.nih.gov/pubmed/28439107
http://dx.doi.org/10.1038/leu.2017.123

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