A case of suspected MPO‐ANCA‐related hypertrophic pachymeningitis with atypical presentation

A 66‐year‐old man presented to our emergency department with acute consciousness disorder, headache, and fever. Initial laboratory data indicated a high level of inflammatory reaction. Enhanced magnetic resonance imaging revealed a thickening of the right cranial dura mater on T1‐weighted images. We...

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Detalles Bibliográficos
Autores principales: Koura, Tomoyuki, Kita, Keiichiro, Konishi, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729363/
https://www.ncbi.nlm.nih.gov/pubmed/29264073
http://dx.doi.org/10.1002/jgf2.73
Descripción
Sumario:A 66‐year‐old man presented to our emergency department with acute consciousness disorder, headache, and fever. Initial laboratory data indicated a high level of inflammatory reaction. Enhanced magnetic resonance imaging revealed a thickening of the right cranial dura mater on T1‐weighted images. We presumed the patient was diagnosed as having myeloperoxidase antineutrophil cytoplasmic antibody (MPO‐ANCA)‐related hypertrophic pachymeningitis (HP). Acute impaired consciousness without focal signs is an unusual presentation of HP. This treatable disease should be considered as a differential diagnosis when a patient presents with drowsiness and headache.

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