Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis

An 82‐year‐old woman with primary biliary cholangitis was diagnosed with an irreversible neurological disorder, caused by metronidazole (MNZ)‐induced encephalopathy. Although the disorder is a reversible pathological condition, in rare cases, it can cause serious sequelae or could even be fatal. The...

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Autores principales: Onuma, Yuki, Oki, Masayuki, Komatsu, Masamichi, Ishitani, Sho, Kijima, Kei, Fukuda, Ryuki, Moriya, Yusuke, Ozawa, Hideki, Takagi, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729387/
https://www.ncbi.nlm.nih.gov/pubmed/29264081
http://dx.doi.org/10.1002/jgf2.91
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author Onuma, Yuki
Oki, Masayuki
Komatsu, Masamichi
Ishitani, Sho
Kijima, Kei
Fukuda, Ryuki
Moriya, Yusuke
Ozawa, Hideki
Takagi, Atsushi
author_facet Onuma, Yuki
Oki, Masayuki
Komatsu, Masamichi
Ishitani, Sho
Kijima, Kei
Fukuda, Ryuki
Moriya, Yusuke
Ozawa, Hideki
Takagi, Atsushi
author_sort Onuma, Yuki
collection PubMed
description An 82‐year‐old woman with primary biliary cholangitis was diagnosed with an irreversible neurological disorder, caused by metronidazole (MNZ)‐induced encephalopathy. Although the disorder is a reversible pathological condition, in rare cases, it can cause serious sequelae or could even be fatal. Therefore, medications should be administered carefully, particularly in patients who require long‐term administration of large doses or those with liver dysfunction.
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spelling pubmed-57293872017-12-20 Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis Onuma, Yuki Oki, Masayuki Komatsu, Masamichi Ishitani, Sho Kijima, Kei Fukuda, Ryuki Moriya, Yusuke Ozawa, Hideki Takagi, Atsushi J Gen Fam Med Case Reports An 82‐year‐old woman with primary biliary cholangitis was diagnosed with an irreversible neurological disorder, caused by metronidazole (MNZ)‐induced encephalopathy. Although the disorder is a reversible pathological condition, in rare cases, it can cause serious sequelae or could even be fatal. Therefore, medications should be administered carefully, particularly in patients who require long‐term administration of large doses or those with liver dysfunction. John Wiley and Sons Inc. 2017-06-21 /pmc/articles/PMC5729387/ /pubmed/29264081 http://dx.doi.org/10.1002/jgf2.91 Text en © 2017 The Authors. Journal of General and Family Medicine published by John Wiley & Sons Australia, Ltd on behalf of Japan Primary Care Association. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Onuma, Yuki
Oki, Masayuki
Komatsu, Masamichi
Ishitani, Sho
Kijima, Kei
Fukuda, Ryuki
Moriya, Yusuke
Ozawa, Hideki
Takagi, Atsushi
Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis
title Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis
title_full Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis
title_fullStr Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis
title_full_unstemmed Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis
title_short Irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis
title_sort irreversible metronidazole encephalopathy in an elderly woman with primary biliary cholangitis
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729387/
https://www.ncbi.nlm.nih.gov/pubmed/29264081
http://dx.doi.org/10.1002/jgf2.91
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