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Cancer incidence in English children, adolescents and young people: past trends and projections to 2030

BACKGROUND: Estimating the future incidence of cancer is important to establish sufficient service provision, however, work in this area is limited for cancer in children, adolescents, and young adults (aged 0–24). METHODS: Age-period-cohort models were applied to cancer incidence rates for the peri...

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Autores principales: Pesola, Francesca, Ferlay, Jacques, Sasieni, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729467/
https://www.ncbi.nlm.nih.gov/pubmed/29096400
http://dx.doi.org/10.1038/bjc.2017.341
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author Pesola, Francesca
Ferlay, Jacques
Sasieni, Peter
author_facet Pesola, Francesca
Ferlay, Jacques
Sasieni, Peter
author_sort Pesola, Francesca
collection PubMed
description BACKGROUND: Estimating the future incidence of cancer is important to establish sufficient service provision, however, work in this area is limited for cancer in children, adolescents, and young adults (aged 0–24). METHODS: Age-period-cohort models were applied to cancer incidence rates for the period 1971–2013 in England. This allowed us to extrapolate past trends to 2030. We used the appropriate cancer classification developed for cancers in children and young adults, which are analysed as two separate groups to capture inherent differences. RESULTS: The data set consisted of 119 485 records (55% among 15+ years group). Overall, cancer rates have increased over time and are expected to continue to rise into the future. Of particular interest is the increase in rates of germ cell tumours (in males) and carcinomas (in females) in young adults, since their rates are projected to further increase over time. CONCLUSIONS: The estimated future incidence rates provide a baseline for different cancer subtypes, which will allow policymakers to develop a contingency plan to deal with future demands.
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spelling pubmed-57294672017-12-15 Cancer incidence in English children, adolescents and young people: past trends and projections to 2030 Pesola, Francesca Ferlay, Jacques Sasieni, Peter Br J Cancer Epidemiology BACKGROUND: Estimating the future incidence of cancer is important to establish sufficient service provision, however, work in this area is limited for cancer in children, adolescents, and young adults (aged 0–24). METHODS: Age-period-cohort models were applied to cancer incidence rates for the period 1971–2013 in England. This allowed us to extrapolate past trends to 2030. We used the appropriate cancer classification developed for cancers in children and young adults, which are analysed as two separate groups to capture inherent differences. RESULTS: The data set consisted of 119 485 records (55% among 15+ years group). Overall, cancer rates have increased over time and are expected to continue to rise into the future. Of particular interest is the increase in rates of germ cell tumours (in males) and carcinomas (in females) in young adults, since their rates are projected to further increase over time. CONCLUSIONS: The estimated future incidence rates provide a baseline for different cancer subtypes, which will allow policymakers to develop a contingency plan to deal with future demands. Nature Publishing Group 2017-12-05 2017-11-02 /pmc/articles/PMC5729467/ /pubmed/29096400 http://dx.doi.org/10.1038/bjc.2017.341 Text en Copyright © 2017 The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Epidemiology
Pesola, Francesca
Ferlay, Jacques
Sasieni, Peter
Cancer incidence in English children, adolescents and young people: past trends and projections to 2030
title Cancer incidence in English children, adolescents and young people: past trends and projections to 2030
title_full Cancer incidence in English children, adolescents and young people: past trends and projections to 2030
title_fullStr Cancer incidence in English children, adolescents and young people: past trends and projections to 2030
title_full_unstemmed Cancer incidence in English children, adolescents and young people: past trends and projections to 2030
title_short Cancer incidence in English children, adolescents and young people: past trends and projections to 2030
title_sort cancer incidence in english children, adolescents and young people: past trends and projections to 2030
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729467/
https://www.ncbi.nlm.nih.gov/pubmed/29096400
http://dx.doi.org/10.1038/bjc.2017.341
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