Anxiety Associated Increased CpG Methylation in the Promoter of Asb1: A Translational Approach Evidenced by Epidemiological and Clinical Studies and a Murine Model

Epigenetic regulation in anxiety is suggested, but evidence from large studies is needed. We conducted an epigenome-wide association study (EWAS) on anxiety in a population-based cohort and validated our finding in a clinical cohort as well as a murine model. In the KORA cohort, participants (n=1522...

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Detalles Bibliográficos
Autores principales: Emeny, Rebecca T, Baumert, Jens, Zannas, Anthony S, Kunze, Sonja, Wahl, Simone, Iurato, Stella, Arloth, Janine, Erhardt, Angelika, Balsevich, Georgia, Schmidt, Mathias V, Weber, Peter, Kretschmer, Anja, Pfeiffer, Liliane, Kruse, Johannes, Strauch, Konstantin, Roden, Michael, Herder, Christian, Koenig, Wolfgang, Gieger, Christian, Waldenberger, Melanie, Peters, Annette, Binder, Elisabeth B, Ladwig, Karl-Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729551/
https://www.ncbi.nlm.nih.gov/pubmed/28540928
http://dx.doi.org/10.1038/npp.2017.102

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