Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole

A patient who never resided in an endemic area for dimorphic fungi was diagnosed with Histoplasma capsulatum endocarditis. His diagnosis was suggested by yeast and hyphae on cardiac valve tissue pathology. Isavuconazole was an optimal therapeutic option due to renal dysfunction and anticoagulation w...

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Autores principales: Wiley, Zanthia, Woodworth, Michael H, Jacob, Jesse T, Lockhart, Shawn R, Rouphael, Nadine G, Gullett, Jonathan C, Guarner, Jeannette, Workowski, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
ID Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729659/
https://www.ncbi.nlm.nih.gov/pubmed/29255737
http://dx.doi.org/10.1093/ofid/ofx241
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author Wiley, Zanthia
Woodworth, Michael H
Jacob, Jesse T
Lockhart, Shawn R
Rouphael, Nadine G
Gullett, Jonathan C
Guarner, Jeannette
Workowski, Kimberly
author_facet Wiley, Zanthia
Woodworth, Michael H
Jacob, Jesse T
Lockhart, Shawn R
Rouphael, Nadine G
Gullett, Jonathan C
Guarner, Jeannette
Workowski, Kimberly
author_sort Wiley, Zanthia
collection PubMed
description A patient who never resided in an endemic area for dimorphic fungi was diagnosed with Histoplasma capsulatum endocarditis. His diagnosis was suggested by yeast and hyphae on cardiac valve tissue pathology. Isavuconazole was an optimal therapeutic option due to renal dysfunction and anticoagulation with warfarin for mechanical valve replacement.
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spelling pubmed-57296592017-12-18 Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole Wiley, Zanthia Woodworth, Michael H Jacob, Jesse T Lockhart, Shawn R Rouphael, Nadine G Gullett, Jonathan C Guarner, Jeannette Workowski, Kimberly Open Forum Infect Dis ID Image A patient who never resided in an endemic area for dimorphic fungi was diagnosed with Histoplasma capsulatum endocarditis. His diagnosis was suggested by yeast and hyphae on cardiac valve tissue pathology. Isavuconazole was an optimal therapeutic option due to renal dysfunction and anticoagulation with warfarin for mechanical valve replacement. Oxford University Press 2017-11-24 /pmc/articles/PMC5729659/ /pubmed/29255737 http://dx.doi.org/10.1093/ofid/ofx241 Text en © The Author(s) 2017. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle ID Image
Wiley, Zanthia
Woodworth, Michael H
Jacob, Jesse T
Lockhart, Shawn R
Rouphael, Nadine G
Gullett, Jonathan C
Guarner, Jeannette
Workowski, Kimberly
Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole
title Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole
title_full Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole
title_fullStr Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole
title_full_unstemmed Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole
title_short Diagnostic Importance of Hyphae on Heart Valve Tissue in Histoplasma Endocarditis and Treatment With Isavuconazole
title_sort diagnostic importance of hyphae on heart valve tissue in histoplasma endocarditis and treatment with isavuconazole
topic ID Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729659/
https://www.ncbi.nlm.nih.gov/pubmed/29255737
http://dx.doi.org/10.1093/ofid/ofx241
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