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Hippo Pathway Deficiency Reverses Systolic Heart Failure Post-Infarction
Mammalian organs vary widely in regenerative capacity. Poorly regenerative organs, such as the heart are particularly vulnerable to organ failure. Once established, heart failure (HF) commonly results in mortality(1). The Hippo pathway, a kinase cascade that prevents adult cardiomyocyte proliferatio...
Autores principales: | Leach, John P., Heallen, Todd, Zhang, Min, Rahmani, Mahdis, Morikawa, Yuka, Hill, Matthew C., Segura, Ana, Willerson, James T., Martin, James F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729743/ https://www.ncbi.nlm.nih.gov/pubmed/28976966 http://dx.doi.org/10.1038/nature24045 |
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