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Hippo Pathway Deficiency Reverses Systolic Heart Failure Post-Infarction

Mammalian organs vary widely in regenerative capacity. Poorly regenerative organs, such as the heart are particularly vulnerable to organ failure. Once established, heart failure (HF) commonly results in mortality(1). The Hippo pathway, a kinase cascade that prevents adult cardiomyocyte proliferatio...

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Detalles Bibliográficos
Autores principales: Leach, John P., Heallen, Todd, Zhang, Min, Rahmani, Mahdis, Morikawa, Yuka, Hill, Matthew C., Segura, Ana, Willerson, James T., Martin, James F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5729743/
https://www.ncbi.nlm.nih.gov/pubmed/28976966
http://dx.doi.org/10.1038/nature24045

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