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Ornithine decarboxylase as a therapeutic target for endometrial cancer
Ornithine Decarboxylase (ODC) a key enzyme in polyamine biosynthesis is often overexpressed in cancers and contributes to polyamine-induced cell proliferation. We noted ubiquitous expression of ODC1 in our published endometrial cancer gene array data and confirmed this in the cancer genome atlas (TC...
Autores principales: | Kim, Hong Im, Schultz, Chad R., Buras, Andrea L., Friedman, Elizabeth, Fedorko, Alyssa, Seamon, Leigh, Chandramouli, Gadisetti V. R., Maxwell, G. Larry, Bachmann, André S., Risinger, John I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730160/ https://www.ncbi.nlm.nih.gov/pubmed/29240775 http://dx.doi.org/10.1371/journal.pone.0189044 |
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