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A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence

Cells and tissues are exposed to stress from numerous sources. Senescence is a protective mechanism that prevents malignant tissue changes and constitutes a fundamental mechanism of aging. It can be accompanied by a senescence associated secretory phenotype (SASP) that causes chronic inflammation. W...

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Detalles Bibliográficos
Autores principales: Meyer, Patrick, Maity, Pallab, Burkovski, Andre, Schwab, Julian, Müssel, Christoph, Singh, Karmveer, Ferreira, Filipa F., Krug, Linda, Maier, Harald J., Wlaschek, Meinhard, Wirth, Thomas, Kestler, Hans A., Scharffetter-Kochanek, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730191/
https://www.ncbi.nlm.nih.gov/pubmed/29206223
http://dx.doi.org/10.1371/journal.pcbi.1005741

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