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Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways

Dysfunction of autophagy, which regulates cellular homeostasis by degrading organelles and proteins, is associated with pathogenesis of various diseases such as cancer, neurodegeneration and metabolic disease. Trehalose, a naturally occurring nontoxic disaccharide found in plants, insects, microorga...

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Detalles Bibliográficos
Autores principales: Mizunoe, Yuhei, Kobayashi, Masaki, Sudo, Yuka, Watanabe, Shukoh, Yasukawa, Hiromine, Natori, Daiki, Hoshino, Ayana, Negishi, Arisa, Okita, Naoyuki, Komatsu, Masaaki, Higami, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730428/
https://www.ncbi.nlm.nih.gov/pubmed/29241092
http://dx.doi.org/10.1016/j.redox.2017.09.007