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Trehalose protects against oxidative stress by regulating the Keap1–Nrf2 and autophagy pathways
Dysfunction of autophagy, which regulates cellular homeostasis by degrading organelles and proteins, is associated with pathogenesis of various diseases such as cancer, neurodegeneration and metabolic disease. Trehalose, a naturally occurring nontoxic disaccharide found in plants, insects, microorga...
Autores principales: | Mizunoe, Yuhei, Kobayashi, Masaki, Sudo, Yuka, Watanabe, Shukoh, Yasukawa, Hiromine, Natori, Daiki, Hoshino, Ayana, Negishi, Arisa, Okita, Naoyuki, Komatsu, Masaaki, Higami, Yoshikazu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730428/ https://www.ncbi.nlm.nih.gov/pubmed/29241092 http://dx.doi.org/10.1016/j.redox.2017.09.007 |
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