SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression

The chaperone protein and guanine nucleotide exchange factor SmgGDS (RAP1GDS1) is a key promoter of cancer cell proliferation and tumorigenesis. SmgGDS undergoes nucleocytoplasmic shuttling, suggesting that it has both cytoplasmic and nuclear functions that promote cancer. Previous studies indicate...

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Detalles Bibliográficos
Autores principales: Gonyo, P, Bergom, C, Brandt, A C, Tsaih, S-W, Sun, Y, Bigley, T M, Lorimer, E L, Terhune, S S, Rui, H, Flister, M J, Long, R M, Williams, C L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730474/
https://www.ncbi.nlm.nih.gov/pubmed/28806394
http://dx.doi.org/10.1038/onc.2017.280

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