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Hybrid splicing minigene and antisense oligonucleotides as efficient tools to determine functional protein/RNA interactions
Alternative splicing is a complex process that provides a high diversity of proteins from a limited number of protein-coding genes. It is governed by multiple regulatory factors, including RNA-binding proteins (RBPs), that bind to specific RNA sequences embedded in a specific structure. The ability...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730568/ https://www.ncbi.nlm.nih.gov/pubmed/29242583 http://dx.doi.org/10.1038/s41598-017-17816-x |