Cargando…
Complement enhances in vitro neutralizing potency of antibodies to human cytomegalovirus glycoprotein B (gB) and immune sera induced by gB/MF59 vaccination
Human cytomegalovirus (HCMV) is the leading cause of in utero viral infection in the United States. Since congenital HCMV infection can lead to birth defects in newborns, developing a prophylactic vaccine is a high priority. One of the early experimental vaccines, composed of a recombinant glycoprot...
Autores principales: | Li, Fengsheng, Freed, Daniel C., Tang, Aimin, Rustandi, Richard R., Troutman, Matthew C., Espeseth, Amy S., Zhang, Ningyan, An, Zhiqiang, McVoy, Michael, Zhu, Hua, Ha, Sha, Wang, Dai, Adler, Stuart P., Fu, Tong-Ming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730571/ https://www.ncbi.nlm.nih.gov/pubmed/29263890 http://dx.doi.org/10.1038/s41541-017-0038-0 |
Ejemplares similares
-
Seronegative patients vaccinated with cytomegalovirus gB-MF59 vaccine have evidence of neutralising antibody responses against gB early post-transplantation
por: Baraniak, Ilona, et al.
Publicado: (2019) -
2772. HCMV gB Ectodomain Subunit and gB mRNA Vaccines Reduce AD-3 Immunodominance and Elicit More Durable Antibody Responses Than gB/MF59 Immunization
por: Nelson, Cody S, et al.
Publicado: (2019) -
The cytomegalovirus gB/MF59 vaccine candidate induces antibodies against an antigenic domain controlling cell-to-cell spread
por: Gomes, A. C., et al.
Publicado: (2023) -
A Native Human Monoclonal Antibody Targeting HCMV gB (AD-2 Site I)
por: McVoy, Michael M., et al.
Publicado: (2018) -
2651. Protection Against Human Cytomegalovirus Acquisition Is Associated with IgG Binding to Cell-Associated CMV glycoprotein B in Two Historical gB/MF59 Vaccine Cohorts
por: Jenks, Jennifer A, et al.
Publicado: (2019)