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The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion
Common genetic variants at the ARL15 locus are associated with plasma adiponectin, insulin and HDL cholesterol concentrations, obesity, and coronary atherosclerosis. The ARL15 gene encodes a small GTP-binding protein whose function is currently unknown. In this study adipocyte-autonomous roles for A...
Autores principales: | Rocha, Nuno, Payne, Felicity, Huang-Doran, Isabel, Sleigh, Alison, Fawcett, Katherine, Adams, Claire, Stears, Anna, Saudek, Vladimir, O’Rahilly, Stephen, Barroso, Inês, Semple, Robert K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730586/ https://www.ncbi.nlm.nih.gov/pubmed/29242557 http://dx.doi.org/10.1038/s41598-017-17746-8 |
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