CK2 modulates adipocyte insulin-signaling and is up-regulated in human obesity

Insulin plays a major role in glucose metabolism and insulin-signaling defects are present in obesity and diabetes. CK2 is a pleiotropic protein kinase implicated in fundamental cellular pathways and abnormally elevated in tumors. Here we report that in human and murine adipocytes CK2-inhibition dec...

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Detalles Bibliográficos
Autores principales: Borgo, Christian, Milan, Gabriella, Favaretto, Francesca, Stasi, Fabio, Fabris, Roberto, Salizzato, Valentina, Cesaro, Luca, Belligoli, Anna, Sanna, Marta, Foletto, Mirto, Prevedello, Luca, Vindigni, Vincenzo, Bardini, Romeo, Donella-Deana, Arianna, Vettor, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730587/
https://www.ncbi.nlm.nih.gov/pubmed/29242563
http://dx.doi.org/10.1038/s41598-017-17809-w

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