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Plant-derived compounds strigolactone GR24 and pinosylvin activate SIRT1 and enhance glucose uptake in rat skeletal muscle cells

Insulin resistance is a characteristic finding in hyperglycaemia and type 2 diabetes. SIRT1 is a NAD(+) dependent deacetylase that plays a central role in glucose homeostasis and energy metabolism. SIRT1 activators, including plant polyphenols such as resveratrol, improve insulin sensitivity in skel...

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Detalles Bibliográficos
Autores principales:	Modi, Shalem, Yaluri, Nagendra, Kokkola, Tarja, Laakso, Markku
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730588/ https://www.ncbi.nlm.nih.gov/pubmed/29242624 http://dx.doi.org/10.1038/s41598-017-17840-x

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