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Synthetic integrin-binding immune stimulators target cancer cells and prevent tumor formation
Immuno-oncology approaches mainly utilize monoclonal antibodies or protein-based scaffolds that bind with high affinity to cancer cells and can generate an immune response. Peptides can also bind with high affinity to cancer cells and are intermediate in size between antibodies and small molecules....
Autores principales: | Brehs, Manuel, Pötgens, André J. G., Steitz, Julia, Thewes, Karine, Schwarz, Janett, Conibear, Anne C., Bartneck, Matthias, Tacke, Frank, Becker, Christian F. W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730604/ https://www.ncbi.nlm.nih.gov/pubmed/29242512 http://dx.doi.org/10.1038/s41598-017-17627-0 |
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