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Signaling of the Complement Cleavage Product Anaphylatoxin C5a Through C5aR (CD88) Contributes to Pharmacological Hematopoietic Stem Cell Mobilization
Several mechanisms have been postulated for orchestrating the mobilization of hematopoietic stem/progenitor cells (HSPCs), and we previously proposed that activation of the complement cascade plays a crucial role in the initiation and execution of the egress of HSPCs from bone marrow (BM) into perip...
Autores principales: | Bujko, Kamila, Rzeszotek, Sylwia, Hoehlig, Kai, Yan, Jun, Vater, Axel, Ratajczak, Mariusz Z. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730632/ https://www.ncbi.nlm.nih.gov/pubmed/28918528 http://dx.doi.org/10.1007/s12015-017-9769-6 |
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