Factors influencing the age at onset in familial frontotemporal lobar dementia: Important weight of genetics

OBJECTIVE: To quantify the effect of genetic factors and generations influencing the age at onset (AAO) in families with frontotemporal lobar dementia (FTD) due to C9ORF72 hexanucleotide repeat expansions and GRN mutations. METHODS: We studied 504 affected individuals from 133 families with C9ORF72...

Descripción completa

Detalles Bibliográficos
Autores principales: Barbier, Mathieu, Camuzat, Agnès, Houot, Marion, Clot, Fabienne, Caroppo, Paola, Fournier, Clémence, Rinaldi, Daisy, Pasquier, Florence, Hannequin, Didier, Pariente, Jérémie, Larcher, Kathy, Brice, Alexis, Génin, Emmanuelle, Sabbagh, Audrey, Le Ber, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730818/
https://www.ncbi.nlm.nih.gov/pubmed/29264395
http://dx.doi.org/10.1212/NXG.0000000000000203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5730818/
https://www.ncbi.nlm.nih.gov/pubmed/29264395
http://dx.doi.org/10.1212/NXG.0000000000000203

Ejemplares similares