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Comparison of Marginal Periosteal Pedicle Graft and Bioactive Glass with Platelet-rich Fibrin and Bioactive Glass in the Treatment of Intrabony Defects – A Clinicoradiographic Study

INTRODUCTION AND OBJECTIVES: The objective of the study was to compare clinically and radiographically the regenerative potential of marginal periosteal pedicle graft (MPPG) or platelet-rich fibrin (PRF) with a bioactive glass in the treatment of two- and three-wall intrabony defects. METHODS: A tot...

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Autores principales: Yasaswini, M. S., Prabhakara Rao, K. V., Tanuja, P., Motakatla, Narendra Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731053/
https://www.ncbi.nlm.nih.gov/pubmed/29284945
http://dx.doi.org/10.4103/jpbs.JPBS_99_17
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author Yasaswini, M. S.
Prabhakara Rao, K. V.
Tanuja, P.
Motakatla, Narendra Reddy
author_facet Yasaswini, M. S.
Prabhakara Rao, K. V.
Tanuja, P.
Motakatla, Narendra Reddy
author_sort Yasaswini, M. S.
collection PubMed
description INTRODUCTION AND OBJECTIVES: The objective of the study was to compare clinically and radiographically the regenerative potential of marginal periosteal pedicle graft (MPPG) or platelet-rich fibrin (PRF) with a bioactive glass in the treatment of two- and three-wall intrabony defects. METHODS: A total of 28 sites (bilateral or contralateral infrabony defects) from 14 patient were treated with MPPG (Experimental site A) and the other site was treated with PRF (Experimental site B). The clinical parameters, such as full-mouth plaque index (PI) and site PI, were recorded at baseline, 3, 6, and 9 months’ postsurgery while sulcus bleeding index (SBI), probing pocket depth (PD), clinical attachment level (CAL), and gingival recession were recorded at baseline, 6, and 9 months. Radiographic evaluation was carried out to evaluate the defect fill, change in alveolar crest height, and percent defect fill at 6 and 9 months. RESULTS: Results showed that both the experimental groups showed clinically and statistically significant reduction in mean PI, SBI, PD, radiographic defect depth, and gain in CAL. The percentage of defect fill at 6 months (70.55 ± 15.99 vs. 55.30 ± 11.87) and 9 months (84.55 ± 11.74 vs. 72.2 ± 9.91) was significantly greater in Site A compared to Site B. CONCLUSIONS: Within the limitations of this study, it can be concluded that both the treatment modalities showed the potential of enhancing bone regeneration. However, the use of marginal periosteal pedicle flap showed better improvement in clinical and radiographic parameters.
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spelling pubmed-57310532017-12-28 Comparison of Marginal Periosteal Pedicle Graft and Bioactive Glass with Platelet-rich Fibrin and Bioactive Glass in the Treatment of Intrabony Defects – A Clinicoradiographic Study Yasaswini, M. S. Prabhakara Rao, K. V. Tanuja, P. Motakatla, Narendra Reddy J Pharm Bioallied Sci Original Article INTRODUCTION AND OBJECTIVES: The objective of the study was to compare clinically and radiographically the regenerative potential of marginal periosteal pedicle graft (MPPG) or platelet-rich fibrin (PRF) with a bioactive glass in the treatment of two- and three-wall intrabony defects. METHODS: A total of 28 sites (bilateral or contralateral infrabony defects) from 14 patient were treated with MPPG (Experimental site A) and the other site was treated with PRF (Experimental site B). The clinical parameters, such as full-mouth plaque index (PI) and site PI, were recorded at baseline, 3, 6, and 9 months’ postsurgery while sulcus bleeding index (SBI), probing pocket depth (PD), clinical attachment level (CAL), and gingival recession were recorded at baseline, 6, and 9 months. Radiographic evaluation was carried out to evaluate the defect fill, change in alveolar crest height, and percent defect fill at 6 and 9 months. RESULTS: Results showed that both the experimental groups showed clinically and statistically significant reduction in mean PI, SBI, PD, radiographic defect depth, and gain in CAL. The percentage of defect fill at 6 months (70.55 ± 15.99 vs. 55.30 ± 11.87) and 9 months (84.55 ± 11.74 vs. 72.2 ± 9.91) was significantly greater in Site A compared to Site B. CONCLUSIONS: Within the limitations of this study, it can be concluded that both the treatment modalities showed the potential of enhancing bone regeneration. However, the use of marginal periosteal pedicle flap showed better improvement in clinical and radiographic parameters. Medknow Publications & Media Pvt Ltd 2017-11 /pmc/articles/PMC5731053/ /pubmed/29284945 http://dx.doi.org/10.4103/jpbs.JPBS_99_17 Text en Copyright: © 2017 Journal of Pharmacy and Bioallied Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Yasaswini, M. S.
Prabhakara Rao, K. V.
Tanuja, P.
Motakatla, Narendra Reddy
Comparison of Marginal Periosteal Pedicle Graft and Bioactive Glass with Platelet-rich Fibrin and Bioactive Glass in the Treatment of Intrabony Defects – A Clinicoradiographic Study
title Comparison of Marginal Periosteal Pedicle Graft and Bioactive Glass with Platelet-rich Fibrin and Bioactive Glass in the Treatment of Intrabony Defects – A Clinicoradiographic Study
title_full Comparison of Marginal Periosteal Pedicle Graft and Bioactive Glass with Platelet-rich Fibrin and Bioactive Glass in the Treatment of Intrabony Defects – A Clinicoradiographic Study
title_fullStr Comparison of Marginal Periosteal Pedicle Graft and Bioactive Glass with Platelet-rich Fibrin and Bioactive Glass in the Treatment of Intrabony Defects – A Clinicoradiographic Study
title_full_unstemmed Comparison of Marginal Periosteal Pedicle Graft and Bioactive Glass with Platelet-rich Fibrin and Bioactive Glass in the Treatment of Intrabony Defects – A Clinicoradiographic Study
title_short Comparison of Marginal Periosteal Pedicle Graft and Bioactive Glass with Platelet-rich Fibrin and Bioactive Glass in the Treatment of Intrabony Defects – A Clinicoradiographic Study
title_sort comparison of marginal periosteal pedicle graft and bioactive glass with platelet-rich fibrin and bioactive glass in the treatment of intrabony defects – a clinicoradiographic study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731053/
https://www.ncbi.nlm.nih.gov/pubmed/29284945
http://dx.doi.org/10.4103/jpbs.JPBS_99_17
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