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Inhibition of the IGF signaling pathway reverses cisplatin resistance in ovarian cancer cells

BACKGROUND: This study was aimed at investigating whether metformin can reverse the resistance of ovarian cancer cells to cisplatin and exploring the underlying mechanism. METHODS: Ovarian cancer cell proliferation in vitro was evaluated using a CCK-8 assay. The resistance index of platinum-resistan...

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Detalles Bibliográficos
Autores principales:	Du, Juan, Shi, Hui-rong, Ren, Fang, Wang, Jing-lu, Wu, Qing-hua, Li, Xia, Zhang, Rui-tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731066/ https://www.ncbi.nlm.nih.gov/pubmed/29241458 http://dx.doi.org/10.1186/s12885-017-3840-1

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