Cargando…

Metachronous and Synchronous Occurrence of 5 Primary Malignancies in a Female Patient between 1997 and 2013: A Case Report with Germline and Somatic Genetic Analysis

The number of patients with multiple primary malignancies has been increasing steadily in recent years. In the present study, we describe a unique case of an 81-year-old woman with 5 metachronous and synchronous primary malignant neoplasms. The patient was first diagnosed with an endometrium adenoca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nyqvist, Jenny, Persson, Fredrik, Parris, Toshima Z., Helou, Khalil, Kenne Sarenmalm, Elisabeth, Einbeigi, Zakaria, Borg, Åke, Karlsson, Per, Kovács, Anikó
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731098/ https://www.ncbi.nlm.nih.gov/pubmed/29279706 http://dx.doi.org/10.1159/000484403

Ejemplares similares

Previously diagnosed multiple primary malignancies in patients with breast carcinoma in Western Sweden between 2007 and 2018
por: Nyqvist, Jenny, et al.
Publicado: (2020)

The prognostic relevance of FOXA1 and Nestin expression in breast cancer metastases: a retrospective study of 164 cases during a 10-year period (2004–2014)
por: De Lara, Shahin, et al.
Publicado: (2019)

Genetic alterations associated with multiple primary malignancies
por: Nyqvist, Jenny, et al.
Publicado: (2021)

Elevated cyclin B2 expression in invasive breast carcinoma is associated with unfavorable clinical outcome
por: Shubbar, Emman, et al.
Publicado: (2013)

Male Breast Carcinoma after Irradiation and Long-Term Phenothiazine Exposure: A Case Report
por: Hultborn, Ragnar, et al.
Publicado: (2020)

Pan-cancer analysis identifies BIRC5 as a prognostic biomarker
por: Fäldt Beding, Anna, et al.
Publicado: (2022)

Prognostic Significance of BIRC5/Survivin in Breast Cancer: Results from Three Independent Cohorts
por: Oparina, Nina, et al.
Publicado: (2021)

Integrative Genomics with Mediation Analysis in a Survival Context
por: Nemes, Szilárd, et al.
Publicado: (2013)

Validation of Novel Prognostic Biomarkers for Early-Stage Clear-Cell, Endometrioid and Mucinous Ovarian Carcinomas Using Immunohistochemistry
por: Engqvist, Hanna, et al.
Publicado: (2020)

Clinical relevance of biomarker discordance between primary breast cancers and synchronous axillary lymph node metastases
por: Janeva, Slavica, et al.
Publicado: (2023)

Trefoil factor family proteins as potential diagnostic markers for mucinous invasive ovarian carcinoma
por: Werner Rönnerman, Elisabeth, et al.
Publicado: (2023)

High levels of γ-glutamyl hydrolase (GGH) are associated with poor prognosis and unfavorable clinical outcomes in invasive breast cancer
por: Shubbar, Emman, et al.
Publicado: (2013)

Clinical relevance of breast cancer-related genes as potential biomarkers for oral squamous cell carcinoma
por: Parris, Toshima Z, et al.
Publicado: (2014)

Integrative genomics approach identifies molecular features associated with early-stage ovarian carcinoma histotypes
por: Engqvist, Hanna, et al.
Publicado: (2020)

Optimization of cell viability assays to improve replicability and reproducibility of cancer drug sensitivity screens
por: Larsson, Peter, et al.
Publicado: (2020)

Pan-cancer analysis of genomic and transcriptomic data reveals the prognostic relevance of human proteasome genes in different cancer types
por: Larsson, Peter, et al.
Publicado: (2022)

Up-regulation of cell cycle arrest protein BTG2 correlates with increased overall survival in breast cancer, as detected by immunohistochemistry using tissue microarray
por: Möllerström, Elin, et al.
Publicado: (2010)

Clonal relatedness in tumour pairs of breast cancer patients
por: Biermann, Jana, et al.
Publicado: (2018)

Immunohistochemical validation of COL3A1, GPR158 and PITHD1 as prognostic biomarkers in early-stage ovarian carcinomas
por: Engqvist, Hanna, et al.
Publicado: (2019)

Paired Primary and Metastatic Tumor Analysis of Somatic Mutations in Synchronous and Metachronous Colorectal Cancer
por: Kim, Kyu-pyo, et al.
Publicado: (2017)

Genomic imbalances and MYB fusion in synchronous bilateral adenoid cystic carcinoma and invasive lobular carcinoma of the breast
por: Kovács, Anikó, et al.
Publicado: (2017)

Transcriptomic and genomic profiling of early-stage ovarian carcinomas associated with histotype and overall survival
por: Engqvist, Hanna, et al.
Publicado: (2018)

Genome-wide multi-omics profiling of the 8p11-p12 amplicon in breast carcinoma
por: Parris, Toshima Z., et al.
Publicado: (2018)

Next-generation sequencing based detection of germline and somatic alterations in a patient with four metachronous primary tumors
por: Martin, Madhuri, et al.
Publicado: (2018)

Synchronous Onset of Breast and Pancreatic Cancers: Results of Germline and Somatic Genetic Analysis
por: Castro, Michael, et al.
Publicado: (2016)

The different clonal origins of metachronous and synchronous metastases
por: Gofrit, Ofer N., et al.
Publicado: (2023)

Mindfulness and its efficacy for psychological and biological responses in women with breast cancer
por: Kenne Sarenmalm, Elisabeth, et al.
Publicado: (2017)

Genetic Profiling Differentiates Second Primary Tumors from Metastases in Adult Metachronous Soft Tissue Sarcoma
por: Fernebro, Josefin, et al.
Publicado: (2008)

Clinical evaluation of molecular surrogate subtypes in patients with ipsilateral multifocal primary breast cancer
por: Janeva, Slavica, et al.
Publicado: (2023)

Bottom-up and top-down approaches to understanding oppositional defiant disorder symptoms during early childhood: a mixed method study
por: Ljungström, Britt-Marie, et al.
Publicado: (2020)

“Since his birth, I’ve always been old” the experience of being parents to children displaying disruptive behavior problems: a qualitative study
por: Ljungström, Britt-Marie, et al.
Publicado: (2020)

Symptoms and Well-Being in Older Hospitalized Patients with Cognitive Impairment, As Self-Reported and Reported in Patient Records: A Quantitative Exploratory Subgroup Analysis
por: Johansson, Yvonne A., et al.
Publicado: (2021)

Distinct microRNA Expression Profiles in Mouse Renal Cortical Tissue after (177)Lu-octreotate Administration
por: Schüler, Emil, et al.
Publicado: (2014)

CHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum
por: Isinger, Anna, et al.
Publicado: (2006)

Fascia iliaca compartment block as a preoperative analgesic in elderly patients with hip fractures – effects on cognition
por: Wennberg, Pär, et al.
Publicado: (2019)

Isolated metachronous splenic metastasis from synchronous colon cancer
por: Gencosmanoglu, Rasim, et al.
Publicado: (2006)

Multicentric Giant Cell Tumor of Bone: Synchronous and Metachronous Presentation
por: Wirbel, Reiner, et al.
Publicado: (2013)

Delirium in older hospitalized patients—signs and actions: a retrospective patient record review
por: Johansson, Yvonne A., et al.
Publicado: (2018)

Effects of internal low-dose irradiation from (131)I on gene expression in normal tissues in Balb/c mice
por: Schüler, Emil, et al.
Publicado: (2011)

Transcriptional response of BALB/c mouse thyroids following in vivo astatine-211 exposure reveals distinct gene expression profiles
por: Rudqvist, Nils, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_jveial8t7jttobjte4sedhbd5b