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FFAR2-FFAR3 receptor heteromerization modulates short-chain fatty acid sensing

Free fatty acid receptors 2 and 3 (FFAR2/FFA2/GPR43 and FFAR3/FFA3/GPR41) are mammalian receptors for gut microbiota–derived short-chain fatty acids (SCFAs). These receptors are promising drug targets for obesity, colitis, colon cancer, asthma, and arthritis. Here, we demonstrate that FFAR2 and FFAR...

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Detalles Bibliográficos
Autores principales:	Ang, Zhiwei, Xiong, Ding, Wu, Min, Ding, Jeak Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731126/ https://www.ncbi.nlm.nih.gov/pubmed/28883043 http://dx.doi.org/10.1096/fj.201700252RR

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