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Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit

A lichenoid drug eruption is a rare side effect which can occur following the administration of several different medications. Here we describe a unique case of fenofibrate as the causative agent of a lichenoid drug eruption. This case highlights a rare and clinically significant dermatologic side e...

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Autores principales: Mohammed, Fayeza, Wally, Laura L., Karaban, Jeffrey E., Reddy, Vijaya B., Lertratanakul, Yongsuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731139/
https://www.ncbi.nlm.nih.gov/pubmed/29282398
http://dx.doi.org/10.1159/000484471
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author Mohammed, Fayeza
Wally, Laura L.
Karaban, Jeffrey E.
Reddy, Vijaya B.
Lertratanakul, Yongsuk
author_facet Mohammed, Fayeza
Wally, Laura L.
Karaban, Jeffrey E.
Reddy, Vijaya B.
Lertratanakul, Yongsuk
author_sort Mohammed, Fayeza
collection PubMed
description A lichenoid drug eruption is a rare side effect which can occur following the administration of several different medications. Here we describe a unique case of fenofibrate as the causative agent of a lichenoid drug eruption. This case highlights a rare and clinically significant dermatologic side effect of fenofibrate. In addition, we report a potential familial association which underscores the potential for underlying genetic mechanisms to be contributory to lichenoid drug eruptions. A reminder of the physical characteristics of lichen planus, knowledge of the temporal relation between administration of medications and a lichenoid drug eruption, recognition of the effect of UV exposure on lichenoid drug eruptions, and realization for the potential of symptoms to persist despite discontinuation of an offending agent can aid practitioners in promptly diagnosing lichenoid drug eruptions and initiating appropriate therapy.
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spelling pubmed-57311392017-12-27 Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit Mohammed, Fayeza Wally, Laura L. Karaban, Jeffrey E. Reddy, Vijaya B. Lertratanakul, Yongsuk Case Rep Dermatol Single Case A lichenoid drug eruption is a rare side effect which can occur following the administration of several different medications. Here we describe a unique case of fenofibrate as the causative agent of a lichenoid drug eruption. This case highlights a rare and clinically significant dermatologic side effect of fenofibrate. In addition, we report a potential familial association which underscores the potential for underlying genetic mechanisms to be contributory to lichenoid drug eruptions. A reminder of the physical characteristics of lichen planus, knowledge of the temporal relation between administration of medications and a lichenoid drug eruption, recognition of the effect of UV exposure on lichenoid drug eruptions, and realization for the potential of symptoms to persist despite discontinuation of an offending agent can aid practitioners in promptly diagnosing lichenoid drug eruptions and initiating appropriate therapy. S. Karger AG 2017-11-14 /pmc/articles/PMC5731139/ /pubmed/29282398 http://dx.doi.org/10.1159/000484471 Text en Copyright © 2017 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Single Case
Mohammed, Fayeza
Wally, Laura L.
Karaban, Jeffrey E.
Reddy, Vijaya B.
Lertratanakul, Yongsuk
Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_full Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_fullStr Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_full_unstemmed Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_short Fenofibrate-Induced Lichenoid Drug Eruption: A Rare Culprit
title_sort fenofibrate-induced lichenoid drug eruption: a rare culprit
topic Single Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731139/
https://www.ncbi.nlm.nih.gov/pubmed/29282398
http://dx.doi.org/10.1159/000484471
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