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Endothelin-1 receptor antagonists protect the kidney against the nephrotoxicity induced by cyclosporine-A in normotensive and hypertensive rats
Cyclosporin-A (CsA) is an immunosuppressant associated with acute kidney injury and chronic kidney disease. Nephrotoxicity associated with CsA involves the increase in afferent and efferent arteriole resistance, decreased renal blood flow (RBF) and glomerular filtration. The aim of this study was to...
Autores principales: | Caires, A., Fernandes, G.S., Leme, A.M., Castino, B., Pessoa, E.A., Fernandes, S.M., Fonseca, C.D., Vattimo, M.F., Schor, N., Borges, F.T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Divulgação Científica
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731326/ https://www.ncbi.nlm.nih.gov/pubmed/29267497 http://dx.doi.org/10.1590/1414-431X20176373 |
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