Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake

Human hepatic lipase (hHL) is mainly localized on the hepatocyte cell surface where it hydrolyzes lipids from remnant lipoproteins and high density lipoproteins and promotes their hepatic selective uptake. Furthermore, hepatic lipase (HL) is closely associated with obesity in multiple studies. There...

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Detalles Bibliográficos
Autores principales: Cedó, Lídia, Santos, David, Roglans, Núria, Julve, Josep, Pallarès, Victor, Rivas-Urbina, Andrea, Llorente-Cortes, Vicenta, Laguna, Joan Carles, Blanco-Vaca, Francisco, Escolà-Gil, Joan Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731695/
https://www.ncbi.nlm.nih.gov/pubmed/29244870
http://dx.doi.org/10.1371/journal.pone.0189834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731695/
https://www.ncbi.nlm.nih.gov/pubmed/29244870
http://dx.doi.org/10.1371/journal.pone.0189834

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