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Natural history of COPD: gaps and opportunities

Understanding the natural history of a disease is as important as knowing its cause(s) for effective disease prevention and treatment. Yet, our current understanding of the natural history of chronic obstructive pulmonary disease (COPD) is incomplete and often controversial. This article discusses t...

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Detalles Bibliográficos
Autores principales: Agustí, Alvar, Celli, Bartolomé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731770/
https://www.ncbi.nlm.nih.gov/pubmed/29255718
http://dx.doi.org/10.1183/23120541.00117-2017
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author Agustí, Alvar
Celli, Bartolomé
author_facet Agustí, Alvar
Celli, Bartolomé
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description Understanding the natural history of a disease is as important as knowing its cause(s) for effective disease prevention and treatment. Yet, our current understanding of the natural history of chronic obstructive pulmonary disease (COPD) is incomplete and often controversial. This article discusses the current gaps, and hence opportunities for research, in this field. In particular, it discusses the following six specific questions. 1) Is COPD a “single” disease? 2) Is COPD “only” a lung disease? 3) When does COPD begin or what is “early” COPD? 4) How does COPD “progress”? 5) How do we assess disease “severity”? 6) Can COPD be prevented (beyond smoking cessation) or its course be modified once detected?
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spelling pubmed-57317702017-12-18 Natural history of COPD: gaps and opportunities Agustí, Alvar Celli, Bartolomé ERJ Open Res Series Understanding the natural history of a disease is as important as knowing its cause(s) for effective disease prevention and treatment. Yet, our current understanding of the natural history of chronic obstructive pulmonary disease (COPD) is incomplete and often controversial. This article discusses the current gaps, and hence opportunities for research, in this field. In particular, it discusses the following six specific questions. 1) Is COPD a “single” disease? 2) Is COPD “only” a lung disease? 3) When does COPD begin or what is “early” COPD? 4) How does COPD “progress”? 5) How do we assess disease “severity”? 6) Can COPD be prevented (beyond smoking cessation) or its course be modified once detected? European Respiratory Society 2017-12-14 /pmc/articles/PMC5731770/ /pubmed/29255718 http://dx.doi.org/10.1183/23120541.00117-2017 Text en Copyright ©ERS 2017 http://creativecommons.org/licenses/by-nc/4.0/ This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Series
Agustí, Alvar
Celli, Bartolomé
Natural history of COPD: gaps and opportunities
title Natural history of COPD: gaps and opportunities
title_full Natural history of COPD: gaps and opportunities
title_fullStr Natural history of COPD: gaps and opportunities
title_full_unstemmed Natural history of COPD: gaps and opportunities
title_short Natural history of COPD: gaps and opportunities
title_sort natural history of copd: gaps and opportunities
topic Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731770/
https://www.ncbi.nlm.nih.gov/pubmed/29255718
http://dx.doi.org/10.1183/23120541.00117-2017
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