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Natural history of COPD: gaps and opportunities
Understanding the natural history of a disease is as important as knowing its cause(s) for effective disease prevention and treatment. Yet, our current understanding of the natural history of chronic obstructive pulmonary disease (COPD) is incomplete and often controversial. This article discusses t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731770/ https://www.ncbi.nlm.nih.gov/pubmed/29255718 http://dx.doi.org/10.1183/23120541.00117-2017 |
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author | Agustí, Alvar Celli, Bartolomé |
author_facet | Agustí, Alvar Celli, Bartolomé |
author_sort | Agustí, Alvar |
collection | PubMed |
description | Understanding the natural history of a disease is as important as knowing its cause(s) for effective disease prevention and treatment. Yet, our current understanding of the natural history of chronic obstructive pulmonary disease (COPD) is incomplete and often controversial. This article discusses the current gaps, and hence opportunities for research, in this field. In particular, it discusses the following six specific questions. 1) Is COPD a “single” disease? 2) Is COPD “only” a lung disease? 3) When does COPD begin or what is “early” COPD? 4) How does COPD “progress”? 5) How do we assess disease “severity”? 6) Can COPD be prevented (beyond smoking cessation) or its course be modified once detected? |
format | Online Article Text |
id | pubmed-5731770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | European Respiratory Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-57317702017-12-18 Natural history of COPD: gaps and opportunities Agustí, Alvar Celli, Bartolomé ERJ Open Res Series Understanding the natural history of a disease is as important as knowing its cause(s) for effective disease prevention and treatment. Yet, our current understanding of the natural history of chronic obstructive pulmonary disease (COPD) is incomplete and often controversial. This article discusses the current gaps, and hence opportunities for research, in this field. In particular, it discusses the following six specific questions. 1) Is COPD a “single” disease? 2) Is COPD “only” a lung disease? 3) When does COPD begin or what is “early” COPD? 4) How does COPD “progress”? 5) How do we assess disease “severity”? 6) Can COPD be prevented (beyond smoking cessation) or its course be modified once detected? European Respiratory Society 2017-12-14 /pmc/articles/PMC5731770/ /pubmed/29255718 http://dx.doi.org/10.1183/23120541.00117-2017 Text en Copyright ©ERS 2017 http://creativecommons.org/licenses/by-nc/4.0/ This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. |
spellingShingle | Series Agustí, Alvar Celli, Bartolomé Natural history of COPD: gaps and opportunities |
title | Natural history of COPD: gaps and opportunities |
title_full | Natural history of COPD: gaps and opportunities |
title_fullStr | Natural history of COPD: gaps and opportunities |
title_full_unstemmed | Natural history of COPD: gaps and opportunities |
title_short | Natural history of COPD: gaps and opportunities |
title_sort | natural history of copd: gaps and opportunities |
topic | Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731770/ https://www.ncbi.nlm.nih.gov/pubmed/29255718 http://dx.doi.org/10.1183/23120541.00117-2017 |
work_keys_str_mv | AT agustialvar naturalhistoryofcopdgapsandopportunities AT cellibartolome naturalhistoryofcopdgapsandopportunities |