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mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis

This study was undertaken to investigate idiopathic pulmonary fibrosis (IPF) patients' health-related quality of life (HRQoL) and symptoms in a real-life cross-sectional study. Our secondary aim was to create a simple identification method for patients with increased need for palliative care by...

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Autores principales: Rajala, Kaisa, Lehto, Juho T., Sutinen, Eva, Kautiainen, Hannu, Myllärniemi, Marjukka, Saarto, Tiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731772/
https://www.ncbi.nlm.nih.gov/pubmed/29255720
http://dx.doi.org/10.1183/23120541.00084-2017
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author Rajala, Kaisa
Lehto, Juho T.
Sutinen, Eva
Kautiainen, Hannu
Myllärniemi, Marjukka
Saarto, Tiina
author_facet Rajala, Kaisa
Lehto, Juho T.
Sutinen, Eva
Kautiainen, Hannu
Myllärniemi, Marjukka
Saarto, Tiina
author_sort Rajala, Kaisa
collection PubMed
description This study was undertaken to investigate idiopathic pulmonary fibrosis (IPF) patients' health-related quality of life (HRQoL) and symptoms in a real-life cross-sectional study. Our secondary aim was to create a simple identification method for patients with increased need for palliative care by studying the relationship between modified Medical Research Council (mMRC) dyspnoea scale, HRQoL and symptoms. We sent a self-rating HRQoL questionnaire (RAND-36) and modified Edmonton Symptom Assessment Scale (ESAS) to 300 IPF patients; 84% of the patients responded to these questionnaires. The most prevalent (>80%) symptoms were tiredness, breathlessness, cough and pain in movement. An increasing mMRC score showed a linear relationship (p<0.001) to impaired HRQoL in all dimensions of RAND-36 and the severity of all symptoms in ESAS. Dimensions of RAND-36 fell below general population reference values in patients with mMRC score ≥2. The intensity of pain in movement (p<0.001) and at rest (p=0.041), and the prevalence of chest pain (p<0.001) had a positive linear relationship to increased mMRC score. An increasing mMRC score reflects impaired HRQoL and a high symptom burden. In clinical practice, the mMRC scale could be used for screening and identification of IPF patients with increased need for palliative care.
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spelling pubmed-57317722017-12-18 mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis Rajala, Kaisa Lehto, Juho T. Sutinen, Eva Kautiainen, Hannu Myllärniemi, Marjukka Saarto, Tiina ERJ Open Res Original Articles This study was undertaken to investigate idiopathic pulmonary fibrosis (IPF) patients' health-related quality of life (HRQoL) and symptoms in a real-life cross-sectional study. Our secondary aim was to create a simple identification method for patients with increased need for palliative care by studying the relationship between modified Medical Research Council (mMRC) dyspnoea scale, HRQoL and symptoms. We sent a self-rating HRQoL questionnaire (RAND-36) and modified Edmonton Symptom Assessment Scale (ESAS) to 300 IPF patients; 84% of the patients responded to these questionnaires. The most prevalent (>80%) symptoms were tiredness, breathlessness, cough and pain in movement. An increasing mMRC score showed a linear relationship (p<0.001) to impaired HRQoL in all dimensions of RAND-36 and the severity of all symptoms in ESAS. Dimensions of RAND-36 fell below general population reference values in patients with mMRC score ≥2. The intensity of pain in movement (p<0.001) and at rest (p=0.041), and the prevalence of chest pain (p<0.001) had a positive linear relationship to increased mMRC score. An increasing mMRC score reflects impaired HRQoL and a high symptom burden. In clinical practice, the mMRC scale could be used for screening and identification of IPF patients with increased need for palliative care. European Respiratory Society 2017-12-14 /pmc/articles/PMC5731772/ /pubmed/29255720 http://dx.doi.org/10.1183/23120541.00084-2017 Text en Copyright ©ERS 2017 http://creativecommons.org/licenses/by-nc/4.0/ This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Original Articles
Rajala, Kaisa
Lehto, Juho T.
Sutinen, Eva
Kautiainen, Hannu
Myllärniemi, Marjukka
Saarto, Tiina
mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis
title mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis
title_full mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis
title_fullStr mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis
title_full_unstemmed mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis
title_short mMRC dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis
title_sort mmrc dyspnoea scale indicates impaired quality of life and increased pain in patients with idiopathic pulmonary fibrosis
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731772/
https://www.ncbi.nlm.nih.gov/pubmed/29255720
http://dx.doi.org/10.1183/23120541.00084-2017
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