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Single-molecule studies contrast ordered DNA replication with stochastic translesion synthesis

High fidelity replicative DNA polymerases are unable to synthesize past DNA adducts that result from diverse chemicals, reactive oxygen species or UV light. To bypass these replication blocks, cells utilize specialized translesion DNA polymerases that are intrinsically error prone and associated wit...

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Detalles Bibliográficos
Autores principales:	Zhao, Gengjing, Gleave, Emma S, Lamers, Meindert Hugo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731819/ https://www.ncbi.nlm.nih.gov/pubmed/29210356 http://dx.doi.org/10.7554/eLife.32177

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