Cargando…

MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9

We investigated the mechanisms by which microRNA (miR)-182 promotes apoptosis and inhibits proliferation in human osteosarcoma (OS) cells. Levels of miR-182 and Homeobox A9 (HOXA9) expression were compared between human OS and normal cells. Subjects were divided into OS and normal groups. We analyze...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Zi-Feng, Wang, Yong-Jian, Fan, Shao-Hua, Du, Shi-Xin, Li, Xue-Dong, Wu, Dong-Mei, Lu, Jun, Zheng, Yuan-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731879/ https://www.ncbi.nlm.nih.gov/pubmed/29254169 http://dx.doi.org/10.18632/oncotarget.21167

Ejemplares similares

Retraction: MicroRNA-182 downregulates Wnt/β-catenin signaling, inhibits proliferation, and promotes apoptosis in human osteosarcoma cells by targeting HOXA9
por: Zhang, Zi-Feng, et al.
Publicado: (2022)

MicroRNA-873 targets HOXA9 to inhibit the aggressive phenotype of osteosarcoma by deactivating the Wnt/β-catenin pathway
por: Liu, Yilin, et al.
Publicado: (2022)

Bufalin Inhibits Proliferation and Induces Apoptosis in Osteosarcoma Cells by Downregulating MicroRNA-221
por: Zhang, Jianjun, et al.
Publicado: (2016)

Down-regulation of microRNA-182 and microRNA-183 predicts progression of osteosarcoma
por: Golbakhsh, Mohammad Reza, et al.
Publicado: (2016)

miR-429 inhibits osteosarcoma progression by targeting HOXA9 through suppressing Wnt/β-catenin signaling pathway
por: Sun, Liangzhi, et al.
Publicado: (2020)

Expression and regulatory effects of microRNA-182 in osteosarcoma cells: A pilot study
por: BIAN, DONG-LIN, et al.
Publicado: (2016)

MicroRNA-638 inhibits the progression of breast cancer through targeting HOXA9 and suppressing Wnt/β-cadherin pathway
por: Xu, Qian, et al.
Publicado: (2021)

HOXA5 inhibits the proliferation and neoplasia of cervical cancer cells via downregulating the activity of the Wnt/β-catenin pathway and transactivating TP53
por: Ma, Hong-Mei, et al.
Publicado: (2020)

In vitro effect of microRNA-107 targeting Dkk-1 by regulation of Wnt/β-catenin signaling pathway in osteosarcoma
por: Zhang, Zhi-Cai, et al.
Publicado: (2017)

Regulatory effects of microRNA-184 on osteosarcoma via the Wnt/β-catenin signaling pathway
por: Du, Zhenguang, et al.
Publicado: (2018)

MicroRNA-186-5p Inhibits Proliferation And Metastasis Of Esophageal Cancer By Mediating HOXA9
por: Xu, Changqin, et al.
Publicado: (2019)

Isoquercitrin restrains the proliferation and promotes apoptosis of human osteosarcoma cells by inhibiting the Wnt/β-catenin pathway
por: Wei, Zhun, et al.
Publicado: (2023)

microRNA-26a-5p Promotes Proliferation and Migration of Osteosarcoma Cells by Targeting HOXA5 in vitro and in vivo
por: Yu, Tianhua, et al.
Publicado: (2019)

MicroRNA-182 downregulates metastasis suppressor 1 and contributes to metastasis of hepatocellular carcinoma
por: Wang, Jian, et al.
Publicado: (2012)

MicroRNA-320a downregulation mediates human liver cancer cell proliferation through the Wnt/β-catenin signaling pathway
por: Lu, Caicheng, et al.
Publicado: (2017)

MicroRNA-505 is downregulated in human osteosarcoma and regulates cell proliferation, migration and invasion
por: Liu, Yu-Jiang, et al.
Publicado: (2018)

Exosome-mediated Hic-5 regulates proliferation and apoptosis of osteosarcoma via Wnt/β-catenin signal pathway
por: Sha, Liansheng, et al.
Publicado: (2020)

microRNA-544 promoted human osteosarcoma cell proliferation by downregulating AXIN2 expression
por: Chen, Ming, et al.
Publicado: (2018)

[Retracted] MicroRNA‑505 is downregulated in human osteosarcoma and regulates cell proliferation, migration and invasion
por: Liu, Yu-Jiang, et al.
Publicado: (2023)

MicroRNA-300 inhibits the growth of hepatocellular carcinoma cells by downregulating CREPT/Wnt/β-catenin signaling
por: Bai, Jinping, et al.
Publicado: (2019)

MicroRNA-140-5p is Downregulated in Osteosarcoma and Overexpression of MicroRNA-140-5p Inhibits Cancer Cell Proliferation by Downregulating GLUT-1
por: Geng, Xiaoling, et al.
Publicado: (2021)

Long Noncoding RNA ZFPM2-AS1 Knockdown Restrains the Development of Retinoblastoma by Modulating the MicroRNA-515/HOXA1/Wnt/β-Catenin Axis
por: Lyv, Xueman, et al.
Publicado: (2020)

Bone protection by inhibition of microRNA-182
por: Inoue, Kazuki, et al.
Publicado: (2018)

Silencing microRNA-27a inhibits proliferation and invasion of human osteosarcoma cells through the SFRP1-dependent Wnt/β-catenin signaling pathway
por: Mu, Yu, et al.
Publicado: (2019)

LncRNA ADAMTS9-AS1 knockdown suppresses cell proliferation and migration in glioma through downregulating Wnt/β-catenin signaling pathway
por: Zhou, Chunhui, et al.
Publicado: (2022)

ETS Proto-Oncogene 1 Suppresses MicroRNA-128 Transcription to Promote Osteogenic Differentiation Through the HOXA13/β-Catenin Axis
por: Li, Renyao, et al.
Publicado: (2021)

MiR-182 regulates cell proliferation and apoptosis in laryngeal squamous cell carcinoma by targeting the CRR9
por: Lv, Yuan, et al.
Publicado: (2019)

MicroRNA-20b Downregulates HIF-1α and Inhibits the Proliferation and Invasion of Osteosarcoma Cells
por: Liu, Ming, et al.
Publicado: (2016)

Targeted deletion of miR-182, an abundant retinal microRNA
por: Jin, Zi-Bing, et al.
Publicado: (2009)

Alantolactone inhibits proliferation, metastasis and promotes apoptosis of human osteosarcoma cells by suppressing Wnt/β-catenin and MAPKs signaling pathways
por: Yang, Chunmei, et al.
Publicado: (2020)

Downregulation of microRNA-182-5p contributes to renal cell carcinoma proliferation via activating the AKT/FOXO3a signaling pathway
por: Xu, Xin, et al.
Publicado: (2014)

Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway
por: Ma, Yunlong, et al.
Publicado: (2015)

OLFML2A Downregulation Inhibits Glioma Proliferation Through Suppression of Wnt/β-Catenin Signaling
por: Ma, Shize, et al.
Publicado: (2021)

microRNA-182 targets special AT-rich sequence-binding protein 2 to promote colorectal cancer proliferation and metastasis
por: Yang, Min-Hui, et al.
Publicado: (2014)

MicroRNA-765 sensitizes osteosarcoma cells to cisplatin via downregulating APE1 expression
por: Liang, Wei, et al.
Publicado: (2019)

LINC01140 regulates osteosarcoma proliferation and invasion by targeting the miR-139-5p/HOXA9 axis
por: Zhang, Shufang, et al.
Publicado: (2022)

MicroRNA-15a-5p inhibits endometrial carcinoma proliferation, invasion and migration via downregulation of VEGFA and inhibition of the Wnt/β-catenin signaling pathway
por: Wang, Honggang, et al.
Publicado: (2021)

Downregulation of human Wnt3 in gastric cancer suppresses cell proliferation and induces apoptosis
por: Wang, Hai-Sheng, et al.
Publicado: (2016)

MicroRNA-885-5p promotes osteosarcoma proliferation and migration by downregulation of cell division cycle protein 73 homolog expression
por: Yu, Feng-Qiang, et al.
Publicado: (2019)

Inhibitory effect of icariin on osteosarcoma cell proliferation via the Wnt/β-catenin signaling pathway
por: Ren, Yuxin, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_u4jb561m4t6hjtovh4uindahmr