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The expression of cystathionine gamma-lyase is regulated by estrogen receptor alpha in human osteoblasts

Hydrogen sulfide (H(2)S), generated in the osteoblasts predominantly via cystathionine-γ-lyase (CSE), is bone protective. Previous studies suggested that the onset of bone loss due to estrogen deficiency is associated to decreased levels of H(2)S and blunted gene expression of CSE. However, there ar...

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Detalles Bibliográficos
Autores principales: Lambertini, Elisabetta, Penolazzi, Letizia, Angelozzi, Marco, Grassi, Francesco, Gambari, Laura, Lisignoli, Gina, De Bonis, Pasquale, Cavallo, Michele, Piva, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731906/
https://www.ncbi.nlm.nih.gov/pubmed/29254196
http://dx.doi.org/10.18632/oncotarget.21514