Profiling of ribonucleotides and deoxyribonucleotides pools in response to DNA damage and repair induced by methyl methanesulfonate in cancer and normal cells

The absolute and relative pool sizes of deoxyribonucleotides (dRNs) are essential in DNA replication fidelity, DNA damage and repair. We found in this study that although DNA damage induced by methyl methanesulfonate (MMS) seemed similar in cancer (HepG2) and normal (LO2) cells, more extensive alter...

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Detalles Bibliográficos
Autores principales: Guo, Jian-Ru, Li, Zheng, Wang, Cai-Yun, Kei Lam, Christopher Wai, Chen, Qian-Qian, Zhang, Wei-Jia, Wai Wong, Vincent Kam, Yao, Mei-Cun, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731908/
https://www.ncbi.nlm.nih.gov/pubmed/29254198
http://dx.doi.org/10.18632/oncotarget.21521

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