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Tomentodione M sensitizes multidrug resistant cancer cells by decreasing P-glycoprotein via inhibition of p38 MAPK signaling

In this study, we investigated the mechanism by which tomentodione M (TTM), a novel natural syncarpic acid-conjugated monoterpene, reversed multi-drug resistance (MDR) in cancer cells. TTM increased the cytotoxicity of chemotherapeutic drugs such as docetaxel and doxorubicin in MCF-7/MDR and K562/MD...

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Detalles Bibliográficos
Autores principales:	Zhou, Xu-Wei, Xia, Yuan-Zheng, Zhang, Ya-Long, Luo, Jian-Guang, Han, Chao, Zhang, Hao, Zhang, Chao, Yang, Lei, Kong, Ling-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731928/ https://www.ncbi.nlm.nih.gov/pubmed/29254218 http://dx.doi.org/10.18632/oncotarget.21949

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