Expression of PD-1/PD-L1 and PD-L2 in peripheral T-cells from non-small cell lung cancer patients

Binding of programmed death-1 (PD-1) with its ligands (PD-L1/2) transmits a co-inhibitory signal in activated T-cells that promotes T-cell exhaustion, leading to tumor immune evasion. The efficacy of antibodies targeting PD-1 and PD-L1 has led to a paradigm shift in lung cancer treatment but the pro...

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Detalles Bibliográficos
Autores principales: Arrieta, Oscar, Montes-Servín, Edgar, Hernandez-Martinez, Juan-Manuel, Cardona, Andrés F., Casas-Ruiz, Eibar, Crispín, José C., Motola, Daniel, Flores-Estrada, Diana, Barrera, Lourdes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731930/
https://www.ncbi.nlm.nih.gov/pubmed/29254220
http://dx.doi.org/10.18632/oncotarget.22025

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