Commensal-infected macrophages induce dedifferentiation and reprogramming of epithelial cells during colorectal carcinogenesis

The colonic microbiome contributes to the initiation of colorectal cancer through poorly characterized mechanisms. We have shown that commensal-polarized macrophages induce gene mutation, chromosomal instability, and endogenous transformation through microbiome-induced bystander effects (MIBE). In t...

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Detalles Bibliográficos
Autores principales: Wang, Xingmin, Yang, Yonghong, Huycke, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731944/
https://www.ncbi.nlm.nih.gov/pubmed/29254234
http://dx.doi.org/10.18632/oncotarget.22250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731944/
https://www.ncbi.nlm.nih.gov/pubmed/29254234
http://dx.doi.org/10.18632/oncotarget.22250

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