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Magnetic resonance imaging of RRx-001 pharmacodynamics in preclinical tumors

RRx-001 is an anticancer agent that subjects cancer cells to reactive oxygen/nitrogen species (ROS/RNS) and acts as an epigenetic modifier. We have used a thiol-bearing MRI contrast agent, Gd-LC7-SH, to investigate the pharmacodynamics of RRx-001 in CHP-100 Ewing's Sarcoma, HT-29 colorectal car...

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Detalles Bibliográficos
Autores principales:	Raghunand, Natarajan, Scicinski, Jan, Guntle, Gerald P., Jagadish, Bhumasamudram, Mash, Eugene A., Bruckheimer, Elizabeth, Oronsky, Bryan, Korn, Ronald L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Clinical Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731976/ https://www.ncbi.nlm.nih.gov/pubmed/29254266 http://dx.doi.org/10.18632/oncotarget.18455

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