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Host species adaptation of TLR5 signalling and flagellin recognition

Toll-like receptor 5 (TLR5) recognition of flagellin instigates inflammatory signalling. Significant sequence variation in TLR5 exists between animal species but its impact on activity is less well understood. Building on our previous research that bovine TLR5 (bTLR5) is functional, we compared huma...

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Detalles Bibliográficos
Autores principales:	Tahoun, Amin, Jensen, Kirsty, Corripio-Miyar, Yolanda, McAteer, Sean, Smith, David G. E., McNeilly, Tom N., Gally, David L., Glass, Elizabeth J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732158/ https://www.ncbi.nlm.nih.gov/pubmed/29247203 http://dx.doi.org/10.1038/s41598-017-17935-5

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