Cargando…

Immediate-Early Genes Modulation by Antipsychotics: Translational Implications for a Putative Gateway to Drug-Induced Long-Term Brain Changes

An increasing amount of research aims at recognizing the molecular mechanisms involved in long-lasting brain architectural changes induced by antipsychotic treatments. Although both structural and functional modifications have been identified following acute antipsychotic administration in humans, c...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Bartolomeis, Andrea, Buonaguro, Elisabetta F., Latte, Gianmarco, Rossi, Rodolfo, Marmo, Federica, Iasevoli, Felice, Tomasetti, Carmine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732183/ https://www.ncbi.nlm.nih.gov/pubmed/29321734 http://dx.doi.org/10.3389/fnbeh.2017.00240

Ejemplares similares

PM437. Spatial and temporal modulation of Homer1a gene expression at the post-synaptic density is related to D2R affinity and dose of antipsychotics: translational considerations for schizophrenia treatment strategies.
por: de Bartolomeis, Andrea, et al.
Publicado: (2016)

S205. A TRANSLATIONAL HOMER 1A-BASED NETWORK APPROACH: IMAGING HOW HALOPERIDOL MODULATES GLUTAMATE SYSTEM FUNCTIONAL CONNECTIVITY
por: Vellucci, Licia, et al.
Publicado: (2020)

F234. TYPICAL AND ATYPICAL ANTIPSYCHOTICS’ D2R AFFINITY AND DOSES INFLUENCES POSTSYNAPTIC DENSITY BY MODULATING THE SPATIAL EXPRESSION OF HOMER1A A GENE HIGHLY IMPLICATED IN SYNAPTIC PLASTICITY AND PSYCHOSIS
por: Camilla, Avagliano, et al.
Publicado: (2018)

Update on the Mechanism of Action of Aripiprazole: Translational Insights into Antipsychotic Strategies Beyond Dopamine Receptor Antagonism
por: de Bartolomeis, Andrea, et al.
Publicado: (2015)

The Glutamatergic Aspects of Schizophrenia Molecular Pathophysiology: Role of the Postsynaptic Density, and Implications for Treatment
por: Iasevoli, Felice, et al.
Publicado: (2014)

A Postsynaptic Density Immediate Early Gene-Based Connectome Analysis of Acute NMDAR Blockade and Reversal Effect of Antipsychotic Administration
por: Barone, Annarita, et al.
Publicado: (2023)

Glycine Signaling in the Framework of Dopamine-Glutamate Interaction and Postsynaptic Density. Implications for Treatment-Resistant Schizophrenia
por: de Bartolomeis, Andrea, et al.
Publicado: (2020)

The Effects of Antipsychotics on the Synaptic Plasticity Gene Homer1a Depend on a Combination of Their Receptor Profile, Dose, Duration of Treatment, and Brain Regions Targeted
por: Iasevoli, Felice, et al.
Publicado: (2020)

Treating the Synapse in Major Psychiatric Disorders: The Role of Postsynaptic Density Network in Dopamine-Glutamate Interplay and Psychopharmacologic Drugs Molecular Actions
por: Tomasetti, Carmine, et al.
Publicado: (2017)

Linking Inflammation, Aberrant Glutamate-Dopamine Interaction, and Post-synaptic Changes: Translational Relevance for Schizophrenia and Antipsychotic Treatment: a Systematic Review
por: de Bartolomeis, Andrea, et al.
Publicado: (2022)

The Neurobiological Underpinnings of Obsessive-Compulsive Symptoms in Psychosis, Translational Issues for Treatment-Resistant Schizophrenia
por: Vellucci, Licia, et al.
Publicado: (2023)

Efficacy and Clinical Determinants of Antipsychotic Polypharmacy in Psychotic Patients Experiencing an Acute Relapse and Admitted to Hospital Stay: Results from a Cross-Sectional and a Subsequent Longitudinal Pilot Study
por: Iasevoli, Felice, et al.
Publicado: (2014)

T226. CLINICAL PREDICTORS OF FUNCTIONAL CAPACITY IN TREATMENT RESISTANT SCHIZOPHRENIA PATIENTS: COMPARISON WITH RESPONDER PATIENTS, ROLE OF NEGATIVE SYMPTOMS, PROBLEM SOLVING DYSFUNCTIONS, AND NEUROLOGICAL SOFT SIGNS
por: Iasevoli, Felice, et al.
Publicado: (2018)

Antipsychotics-Induced Changes in Synaptic Architecture and Functional Connectivity: Translational Implications for Treatment Response and Resistance
por: de Bartolomeis, Andrea, et al.
Publicado: (2022)

Dopamine Dynamics and Neurobiology of Non-Response to Antipsychotics, Relevance for Treatment Resistant Schizophrenia: A Systematic Review and Critical Appraisal
por: Iasevoli, Felice, et al.
Publicado: (2023)

The Role of Inhaled Loxapine in the Treatment of Acute Agitation in Patients with Psychiatric Disorders: A Clinical Review
por: de Berardis, Domenico, et al.
Publicado: (2017)

O9.4. RELATIONSHIPS BETWEEN AGE AT ONSET OF PSYCHOTIC SYMPTOMS AND POOR RESPONSE TO ANTIPSYCHOTICS IN A SAMPLE OF TRS/NON-TRS PATIENTS
por: Iasevoli, Felice, et al.
Publicado: (2020)

The Melatonergic System in Mood and Anxiety Disorders and the Role of Agomelatine: Implications for Clinical Practice
por: De Berardis, Domenico, et al.
Publicado: (2013)

S228. TOWARD EARLY DETECTION OF TREATMENT RESISTANT SCHIZOPHRENIA: PREDICTIVE INFORMATION ON NON-RESPONSE TO ANTIPSYCHOTICS BY EVALUATION OF A FEW CLINICAL FACTORS: A STUDY BY ROC CURVE ANALYSIS AND CONFIRMATORY MULTIVARIATE ANALYSIS
por: Iasevoli, Felice, et al.
Publicado: (2018)

Lurasidone in the Treatment of Bipolar Depression: Systematic Review of Systematic Reviews
por: Fornaro, Michele, et al.
Publicado: (2017)

Tobacco smoking in treatment-resistant schizophrenia patients is associated with impaired cognitive functioning, more severe negative symptoms, and poorer social adjustment
por: Iasevoli, Felice, et al.
Publicado: (2013)

Schizophrenia Synaptic Pathology and Antipsychotic Treatment in the Framework of Oxidative and Mitochondrial Dysfunction: Translational Highlights for the Clinics and Treatment
por: De Simone, Giuseppe, et al.
Publicado: (2023)

Agomelatine beyond Borders: Current Evidences of Its Efficacy in Disorders Other than Major Depression
por: De Berardis, Domenico, et al.
Publicado: (2015)

Suicide during Perinatal Period: Epidemiology, Risk Factors, and Clinical Correlates
por: Orsolini, Laura, et al.
Publicado: (2016)

Dysregulated Signaling at Postsynaptic Density: A Systematic Review and Translational Appraisal for the Pathophysiology, Clinics, and Antipsychotics’ Treatment of Schizophrenia
por: de Bartolomeis, Andrea, et al.
Publicado: (2023)

Predicting the Severity of Lockdown-Induced Psychiatric Symptoms with Machine Learning
por: D’Urso, Giordano, et al.
Publicado: (2022)

Neural substrates of verbal memory impairment in schizophrenia: A multimodal connectomics study
por: Tranfa, Mario, et al.
Publicado: (2023)

Gateway to Japan
por: Kinoshita, June
Publicado: (1990)

"On guard at the gateway".
por: Taggart, J. M.
Publicado: (1967)

Gateways into electronics
por: Dunn, Peter Carroll
Publicado: (2000)

S3 Gateway
por: Hanushevsky, Andrew Bohdan
Publicado: (2023)

The Gateways of Medicines
Publicado: (1890)

Canonical and Non-Canonical Antipsychotics’ Dopamine-Related Mechanisms of Present and Next Generation Molecules: A Systematic Review on Translational Highlights for Treatment Response and Treatment-Resistant Schizophrenia
por: de Bartolomeis, Andrea, et al.
Publicado: (2023)

From Gateway to MultiSite Gateway in one recombination event
por: Magnani, Enrico, et al.
Publicado: (2006)

M170. GENETIC CHARACTERIZATION OF A COHORT OF PATIENTS AFFECTED BY SCHIZOPHRENIA. THE ROLE FOR RARE STRUCTURAL VARIANTS IN MODULATING TREATMENT RESISTANT ENDOPHENOTYPES: PRELIMINARY DATA
por: Barone, Annarita, et al.
Publicado: (2020)

Weight Gain, Schizophrenia and Antipsychotics: New Findings from Animal Model and Pharmacogenomic Studies
por: Panariello, Fabio, et al.
Publicado: (2011)

Predictors of Treatment Resistance Across Different Clinical Subtypes of Depression: Comparison of Unipolar vs. Bipolar Cases
por: Fornaro, Michele, et al.
Publicado: (2020)

Psychological distress in patients with serious mental illness during the COVID-19 outbreak and one-month mass quarantine in Italy
por: Iasevoli, Felice, et al.
Publicado: (2020)

Customized Additive Manufacturing in Bone Scaffolds—The Gateway to Precise Bone Defect Treatment
por: Zhou, Juncen, et al.
Publicado: (2023)

Evolution of the Gateway Services
por: Popescu, Radu
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_51gel92bsi4b6ifs50hed9lj9m