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Baculovirus-assisted Reovirus Infection in Monolayer and Spheroid Cultures of Glioma cells

The mammalian orthoreovirus Type 3 Dearing has great potential as oncolytic agent in cancer therapy. One of the bottlenecks that hampers its antitumour efficacy in vivo is the limited tumour-cell infection and intratumoural distribution. This necessitates strategies to improve tumour penetration. In...

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Detalles Bibliográficos
Autores principales:	Dautzenberg, Iris J. C., van den Hengel, Sanne K., de Vrij, Jeroen, Ravesloot, Lars, Cramer, Steve J., Hong, Saw-See, van den Wollenberg, Diana J. M., Boulanger, Pierre, Hoeben, Rob C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732240/ https://www.ncbi.nlm.nih.gov/pubmed/29247249 http://dx.doi.org/10.1038/s41598-017-17709-z

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