Leukotriene B(4) is essential for lung host defence and alpha-defensin-1 production during Achromobacter xylosoxidans infection

Leukotriene B(4) (LTB(4)) is essential for host immune defence. It increases neutrophil recruitment, phagocytosis and pathogen clearance, and decreases oedema and inflammasome activation. The host response and the role of LTB(4) during Achromobacter xylosoxidans infection remain unexplored. Wild-typ...

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Detalles Bibliográficos
Autores principales: Prado, Morgana K. B., Locachevic, Gisele A., Zoccal, Karina F., Paula-Silva, Francisco W. G., Fontanari, Caroline, Ferreira, Joseane C., Pereira, Priscilla A. T., Gardinassi, Luiz G., Ramos, Simone G., Sorgi, Carlos A., Darini, Ana Lúcia C., Faccioli, Lúcia H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732241/
https://www.ncbi.nlm.nih.gov/pubmed/29247243
http://dx.doi.org/10.1038/s41598-017-17993-9

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