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Phospholipid flipping involves a central cavity in P4 ATPases

P4 ATPase flippases translocate phospholipids across biomembranes, thus contributing to the establishment of transmembrane lipid asymmetry, a feature important for multiple cellular processes. The mechanism by which such phospholipid flipping occurs remains elusive as P4 ATPases transport a giant su...

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Detalles Bibliográficos
Autores principales:	Jensen, M. S., Costa, S. R., Duelli, A. S., Andersen, P. A., Poulsen, L. R., Stanchev, L. D., Gourdon, P., Palmgren, M., Günther Pomorski, T., López-Marqués, R. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732287/ https://www.ncbi.nlm.nih.gov/pubmed/29247234 http://dx.doi.org/10.1038/s41598-017-17742-y

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