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She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain
Cytoplasmic dynein is an enormous minus end-directed microtubule motor. Rather than existing as bare tracks, microtubules are bound by numerous microtubule-associated proteins (MAPs) that have the capacity to affect various cellular functions, including motor-mediated transport. One such MAP is She1...
Autores principales: | Ecklund, Kari H., Morisaki, Tatsuya, Lammers, Lindsay G., Marzo, Matthew G., Stasevich, Timothy J., Markus, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732302/ https://www.ncbi.nlm.nih.gov/pubmed/29247176 http://dx.doi.org/10.1038/s41467-017-02004-2 |
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