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She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain

Cytoplasmic dynein is an enormous minus end-directed microtubule motor. Rather than existing as bare tracks, microtubules are bound by numerous microtubule-associated proteins (MAPs) that have the capacity to affect various cellular functions, including motor-mediated transport. One such MAP is She1...

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Detalles Bibliográficos
Autores principales: Ecklund, Kari H., Morisaki, Tatsuya, Lammers, Lindsay G., Marzo, Matthew G., Stasevich, Timothy J., Markus, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732302/
https://www.ncbi.nlm.nih.gov/pubmed/29247176
http://dx.doi.org/10.1038/s41467-017-02004-2

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