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SOX30 is required for male fertility in mice
Male infertility is a major and growing problem and, in most cases, the specific root cause is unknown. Here we show that the transcription factor SOX30 plays a critical role in mouse spermatogenesis. Sox30-null mice are healthy and females are fertile, but males are sterile. In the absence of Sox30...
Autores principales: | Feng, Chun-Wei Allen, Spiller, Cassy, Merriner, Donna J., O’Bryan, Moira K., Bowles, Josephine, Koopman, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732304/ https://www.ncbi.nlm.nih.gov/pubmed/29247201 http://dx.doi.org/10.1038/s41598-017-17854-5 |
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